It was confirmed in an interview with Fuse that Lil B is working with Drake. Here is a excerpt from the interview.
“Yeah, we’re about to do something real big. I can’t speak on it too much right now, but Drake is the only artist [Lil B] wants to work with. We’ve talked about doing some production.”
Lil B added, “[Drake] wants to do something and we’re gonna make it happen. Something real big, so just look out for it.”